FASI 2023 Symposium
Immune Tolerance at the Barrier Interface
May 19th, 2023
The Broad Institute of MIT & Harvard
Symposium Agenda
8:00 – 8:45 am
Registration & Breakfast
8:45 – 8:50 am
Opening Remarks
Carlos Bosques, PhD, FASI
Carlos Bosques, PhD, FASI
8:45 – 8:50 am
FASI Scientific Overview
Ruslan Medzhitov, PhD
Yale School of Medicine
Ruslan Medzhitov, PhD
Yale School of Medicine
Session 1: Tolerance at the Gut Barrier
9:00 – 9:30am
Barrier Defense – Insights from Genetics
Ramnik Xavier, MD, PhD
Broad Institute of MIT and Harvard
Ramnik Xavier, MD, PhD
Broad Institute of MIT and Harvard
9:30 – 10:00am
The Peyer’s Patches Sense, Enhance and Transmit Probiotic Signals Important for Homeostasis
Mia Phillipson, PhD
Uppsala University of Sweden
Mia Phillipson, PhD
Uppsala University of Sweden
10:00 – 10:30am
Microbiota-Directed Immune Tolerance at the Gut Barrier
Dan Littman, MD, PhD
New York University School of Medicine
Dan Littman, MD, PhD
New York University School of Medicine
10:30 -10:45am
Break
Session 2: Tolerance at the Skin Barrier
10:45 – 11:15am
On-Person Adaptive Evolution of Staphylococcus Aureus during Treatment for Atopic Dermatitis
Tami Lieberman, PhD
Massachusetts Institute of Technology
Tami Lieberman, PhD
Massachusetts Institute of Technology
11:15 – 11:45am
Tracking the Fate of Food Antigen-Specific Helper T cells
Marc Jenkins, PhD
University of Minnesota Medical School
Marc Jenkins, PhD
University of Minnesota Medical School
11:45 – 12:15pm
Sensing Inflammation in the Skin and Beyond
Brian Kim, MD
Icahn School of Medicine at Mount Sinai
Brian Kim, MD
Icahn School of Medicine at Mount Sinai
12:15 -1:15pm
Lunch Break
Session 3: Potential for Tolerogenic Therapies
1:15 – 1:45pm
A Tale of Two Strategies to Mitigate Peanut Allergy in Mice
Kei Kishimoto, PhD
Selecta Biosciences
Kei Kishimoto, PhD
Selecta Biosciences
1:45 – 2:15pm
Treg Cells as Mediators of Intestinal Tolerance
Alexander Rudensky, PhD
Memorial Sloan Kettering Cancer Center
Alexander Rudensky, PhD
Memorial Sloan Kettering Cancer Center
2:15 – 2:45pm
Induction of Tregs by Mucosal Administration of Anti-CD3 mAb to Treat Inflammatory and Autoimmune Diseases
Howard Weiner, MD
Harvard Medical School
Howard Weiner, MD
Harvard Medical School
2:45 -3:00pm
Break
Session 4: FASI Spotlight
3:00 – 4:00pm
Presentations from FASI Lab Members
Karen Agaronyan
Medzhitov Lab, Yale University
Michael Schappe
Liberles Lab, Harvard Medical School
Emily Siniscalco
Eisenbarth Lab, Yale University
Peng Tan
Xavier Lab, Broad Institute of MIT and Harvard
Daniel Waizman
Wang Lab, Yale University
Karen Agaronyan
Medzhitov Lab, Yale University
Michael Schappe
Liberles Lab, Harvard Medical School
Emily Siniscalco
Eisenbarth Lab, Yale University
Peng Tan
Xavier Lab, Broad Institute of MIT and Harvard
Daniel Waizman
Wang Lab, Yale University
Closing Remarks & Poster Session
4:00 – 4:15 pm
Closing Remarks
Ruslan Medzhitov, PhD
Yale School of Medicine
Ruslan Medzhitov, PhD
Yale School of Medicine
4:30 – 6:00 pm
Poster Session & Cocktail Reception
Speakers
Ruslan Medzhitov, PhD, Yale School of Medicine
Ramnik Xavier, MD, PhD, Broad Institute of MIT and Harvard
Dan Littman, MD, PhD, New York University School of Medicine
Marc Jenkins, PhD, University of Minnesota Medical School
Kei Kishimoto, PhD, Selecta Biosciences
Howard Weiner, MD, Harvard Medical School
Juan J. Lafaille, PhD, New York University School of Medicine
Alexander Rudensky, PhD, Memorial Sloan Kettering Cancer Center
Tami Lieberman, PhD, Massachusetts Institute of Technology