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Catalyzing change

Since 2015, FASI has been hosting symposiums to showcase our scientists' cutting edge allergy research

2023 Symposium - Immune Tolerance at the Barrier Interface

8:00 – 8:45 am
Registration & Breakfast
8:45 – 8:50 am
Opening Remarks Carlos Bosques, PhD,
FASI
8:45 – 8:50 am
FASI Scientific Overview Ruslan
Medzhitov, PhD Yale School of Medicine

Session 1: Tolerance at the Gut Barrier

9:00 – 9:30am
Barrier Defense – Insights from Genetics
Ramnik Xavier, MD, PhD Broad Institute of MIT and Harvard
9:30 – 10:00am
The Peyer’s Patches Sense, Enhance and Transmit Probiotic Signals
Important for Homeostasis
Mia Phillipson, PhD Uppsala University of Sweden
10:00 – 10:30am
Microbiota-Directed Immune Tolerance at the Gut Barrier
Dan Littman, MD, PhD New York University School of Medicine
10:30 -10:45am

Break

Session 2: Tolerance at the Skin Barrier

10:45 – 11:15am
On-Person Adaptive Evolution of Staphylococcus Aureus during Treatment
for Atopic Dermatitis
Tami Lieberman, PhD Massachusetts Institute of Technology
11:15 – 11:45am
Tracking the Fate of Food Antigen-Specific Helper T cells
Marc Jenkins, PhD University of Minnesota Medical School
11:45 – 12:15pm
Sensing Inflammation in the Skin and Beyond
Brian Kim, MD Icahn School of Medicine at Mount Sinai
12:15 -1:15pm

Lunch Break

Session 3: Potential for Tolerogenic Therapies

1:15 – 1:45pm
A Tale of Two Strategies to Mitigate Peanut Allergy in Mice
Kei Kishimoto, PhD Selecta Biosciences
1:45 – 2:15pm
Treg Cells as Mediators of Intestinal Tolerance
Alexander Rudensky, PhD Memorial Sloan Kettering Cancer Center
2:15 – 2:45pm
Induction of Tregs by Mucosal Administration of Anti-CD3 mAb to Treat
Inflammatory and Autoimmune Diseases
Howard Weiner, MD Harvard Medical School
2:45 -3:00pm

Break

Session 4: FASI Spotlight

3:00 – 4:00pm
Presentations from FASI Lab Members
Karen Agaronyan
Medzhitov Lab, Yale University
Michael Schappe
Liberles Lab, Harvard Medical School
Emily Siniscalco
Eisenbarth Lab, Yale University
Peng Tan
Xavier Lab, Broad Institute of MIT and Harvard
Daniel Waizman
Wang Lab, Yale University

Closing Remarks & Poster Session

4:00 – 4:15 pm
Closing Remarks Ruslan Medzhitov,
PhD Yale School of Medicine
4:30 – 6:00 pm
Poster Session & Cocktail Reception

Download 2023 FASI Symposium Agenda

Speakers

Ruslan Medzhitov, PhD, Yale School of Medicine

Ramnik Xavier, MD, PhD, Broad Institute of MIT and Harvard

Dan Littman, MD, PhD, New York University School of Medicine

Marc Jenkins, PhD, University of Minnesota Medical School

Kei Kishimoto, PhD, Selecta Biosciences

Howard Weiner, MD, Harvard Medical School

Juan J. Lafaille, PhD, New York University School of Medicine

Alexander Rudensky, PhD, Memorial Sloan Kettering Cancer Center Tami
Lieberman, PhD, Massachusetts Institute of Technology

Patron ($10,000)

Benefactor ($5,000)

Food Biology in Health and Disease

8:00 am
Registration & Breakfast
8:45 am
Opening remarks
Ruslan Medzhitov, PhD, Yale School of Medicine
9:00 – 10:30 am
Session 1: Diet, Microbiome, and Immunity
Yasmine Belkaid, PhD, National Institutes of Health
Michiko Oyoshi, PhD, Massachusetts General Hospital
Jeffrey Gordon, MD, Washington University School of Medicine
10:45 – 12:15 pm
Session 2: Gut Mucosa Biology
Daria Esterhazy, PhD, University of Chicago
Irene Salinas, PhD, University of New Mexico
Malin Johansson, PhD, University of Gothenburg
1:15 – 2:30 pm
Session 3: FASI Research Spotlight
Cameron Flayer, PhD, Harvard Medical School
Rocky Barilla, BS, Harvard Medical School
Daping Yang, PhD, Harvard Medical School
Anna Eisenstein, MD, PhD, Yale School of Medicine
2:30 – 4:00 pm
Session 4: Type 2 Immune Responses
Cecilia Berin, PhD, Icahn School of Medicine at Mount Sinai
De’Broski Herbert, PhD, University of Pennsylvania
William Gause, PhD, Rutgers University
4:00 pm
Closing remarks
Ruslan Medzhitov, PhD, Yale School of Medicine
4:30 – 6:00 pm
Poster Session & Reception

Sponsors

Food Biology in Health and Disease

11:00 AM – 11:15 AM
Opening remarks
Ruslan Medzhitov, Ph.D., Yale University
11:15 AM – 11:45 AM
Nutritional priorities for health: New scientific directions
Dariush Mozaffarian, M.D., Dr.PH., Tufts Friedman School of Nutrition Science and Policy
11:45 AM – 12:15 PM
Discovery and engineering of plant chemistry for plant and human health
Elizabeth Sattely, Ph.D., Stanford University
12:15 PM – 12:45 PM
Dietary fiber and mucus-degrading bacteria in health and disease
Eric C. Martens, Ph.D., University of Michigan Medical School
12:45 PM – 1:15 PM
Mapping uncharted landscapes of host-microbiota connectivity
Noah Palm, Ph.D., Yale University School of Medicine
1:15 PM – 1:45 PM
Break
1:45 PM – 2:15 PM
Mechanisms of oral tolerance breakdown in food allergy
Talal A. Chatila, M.D., Boston Children’s Hospital
2:15 PM – 2:45 PM
Immune responses to dietary antigen
Bana Jabri, M.D., Ph.D., University of Chicago
2:45 PM – 3:15 PM
Internal organ sensory systems
Stephen D. Liberles, Ph.D., Harvard Medical School
3:15 PM – 3:45 PM
A subliminal sense for calories
Diego V. Bohorquez, Ph.D., Duke University School of Medicine
3:45 PM – 4:00 PM
Closing remarks
Ruslan Medzhitov, Ph.D., Yale University

Neuro-immune Communications

8:00 am – 9:00 am
Registration & breakfast
9:00 am – 9:15 am
Opening remarks
Ruslan Medzhitov, Ph.D., Yale University
9:15 am – 10:00 am
Keynote: The Neural basis of sugar craving
Charles Zuker, Ph.D., Columbia University
10:00 am – 10:30 am
The Gut-Brain Axis and Reward
Ivan De Araujo, DPhil, Icahn School of Medicine at Mount Sinai
10:30 am – 10:45 am
Break
10:45 am – 11:15 am
Neuro-immune interactions in the gut
Daniel Mucida, Ph.D., The Rockefeller University
11:15 am – 11:45 am
Neuronal Regulation of Innate Lymphoid Cells
Henrique Veiga-Fernandes, Ph.D., Champalimaud Centre for the
Unknown
11:45 am – 12:15 pm
Regulation of intestinal inflammation
David Artis, Ph.D., Weill Cornell Medical College
12:15 pm – 1:00 pm
Lunch
1:00 pm – 1:15 pm
Short talk: Neuroimmune Loops in the Initiation of Allergic Immune
Responses
Caroline Sokol, M.D., Ph.D., Massachusetts General Hospital
1:15 pm – 1:45 pm
Innate immune mechanisms regulating brain development
Anna Molofsky, M.D., Ph.D., University of California, San Francisco
1:45 pm – 2:15 pm
Microglia Diversity and Function in Health & Disease
Beth Stevens, Ph.D., Boston Children’s Hospital
2:15 pm – 2:30 pm
Break
2:30 pm – 2:45 pm
Lightning talk: CGRP negatively regulates alarmin-driven ILC2 responses
Antonia Wallrapp, Brigham and Women’s Hospital
2:45 pm – 3:15 pm
Neuron atlases as roadmaps to disease
Aviv Regev, Ph.D., Broad Institute
3:15 pm – 4:00 pm
Keynote: Nociceptor driven inflammation
Clifford Woolf, Ph.D., Boston Children’s Hospital
4:00 – 4:05 pm
Closing remarks
4:05 pm – 6:00 pm
Poster session & reception

What Feeds Allergies?

7:30 am – 8:30 am
Registration & Breakfast
8:30 am – 8:45 am
Opening remarks
Eric S. Lander, Ph.D., Broad Institute
8:45 am – 9:30 am
Keynote: Ecological perspectives on food allergy
Ruslan Medzhitov, Ph.D.,
Yale University
9:30 am – 10:00 am
Break
10:00 am – 10:30 am
Precision medicine in food allergy: challenges and opportunities
Stephen J.
Galli, M.D.,
Stanford University School
of Medicine
10:30 am – 11:00 am
Mechanisms of food OIT
Kari Nadeau, M.D., Ph.D., Stanford University
11:00 am – 11:30 am
Food allergen thresholds and quantitative risk assessment: putting the science into
practice
Joseph Baumert, Ph.D.,
University of Nebraska-Lincoln
11:30 am – 12:00 pm
Pathoetiology and genetics of recently emerging new food allergy disorder eosinophilic
esophagitis
Marc E.
Rothenberg M.D., Ph.D., Cincinnati Children’s Hospital Medical Center
12:00 pm – 12:45 pm
Lunch
12:45pm – 1:30pm
Keynote: Innate allergy
Richard M. Locksley, M.D., University of
California, San Francisco
1:30 pm – 2:00 pm
Immune profiling of pediatric food allergic cohorts
M. Cecilia Berin, Ph.D.,

Icahn School of Medicine at Mount
Sinai
2:00 pm – 2:30 pm
Insights into the regulation of IgE B cells
Duane Wesemann, M.D., Ph.D.,
Brigham and Women’s Hospital
2:30pm – 3:00pm
Protective antibody induction in peanut oral immunotherapy
Sarita Patil, M.D.,
Massachusetts General Hospital
3:00 -3:30pm
Break
3:30 pm – 4:00 pm
Proactive management of food allergy
Stephanie Blum, Ph.D., Nestlé Health
Science
4:00 pm – 4:30 pm
Finding cures for food allergy from traditional herbal medicine
Jing-ke Weng,
Ph.D., Whitehead Institute
4:30 pm – 5:30 pm
Reception

Symposium 2015: Current State of Food Allergy Research

7:30 – 8:00
Breakfast
8:00 – 8:30
Overview
David Altshuler, Vertex Pharmaceutials
8:30 – 9:00
State-of-the-State in Food Allergy Research: Basic to Translational
Talal Chatila, Boston Children’s Hospital
9:00 – 9:30
State-of-the-State in Food Allergy Research: Translational to Clinical
Wayne Shretfler, Massachusetts General Hospital
9:30 – 10:00
Understanding the Role of Genetics and the Microbiome: Lessons from IBD
Ramnik Xavier, Massachusetts CieneraI Hospital
10:00 – 10:30
Break
10:30 – 11:00
Deciphering Immune Circuitry: From Autoimmunity to Food Allergy Regulation of Th2 Response by Regulatory T Cells
Aviv Regev, Broad institute/MIT
11:00 – 11:30
Regulation of Th2 Response by Regulatory T Cells
Vijay Kuchroo, Brigham and Women’s Hospital
11:30 – 12:30
Lunch
12:30 – 1:00
Elucidating Allergen-induced Immune Responses
Ruslan Medzhitoy, Yale University
1:00 – 1:30
Synthetic Vaccine Particles for Immune Modulation and Immune Tolerance
Kei Kishimoto, Selecta Biosciences